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编 号:F746082
分子式:C19H12BrN3O2
分子量:394.22
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生物活性:
COX-2-IN-16 (compound 2b) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 102 μM. COX-2-IN-16 inhibits the NO production. COX-2-IN-16 shows anti-inflammatory activity.

体内研究:
COX-2-IN-16 (compound 2b) (100 mg/kg; p.o.) shows better reduction in the edema formation by 42% in a rat paw edema model.
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