产品
编 号:F745812
分子式:C29H36BrN5O4
分子量:598.53
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规格
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1mg
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询价
5mg
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产品详情
生物活性:
SM-1295 is an inhibitor of apoptosis protein (IAP) antagonist, with Kd values of 3077 nM, 3.2 nM and 9.5 nM for XIAP-BIR3, c-IAP1-BIR3 and c-IAP2-BIR3, respectively.

体外研究:
SM-1295 (compound 5) binds to both cIAP1 and cIAP2 proteins with Ki values of 900-fold for cIAP1 over XIAP.SM-1295 (compound 5) exhibits an IC50 of 46 nM in MDA-MB-231.
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