产品
编 号：F745805
分子式：C14H15NO2S2
分子量：293.4
分子式：C14H15NO2S2
分子量：293.4
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
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询价
结构图
CAS No: 1558598-48-3
产品详情
生物活性：
PFM03 is a MRE11 Endonuclease inhibitor. PFM03 regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ).
体外研究：
PFM03 (50-400 μM; 30 min) specifically inhibits MRE11 endonuclease activity.PFM03 (100 μM; 30 min) causes normal DSB repair in G2 (CENPF+) cells.PFM03 (50 μM; 8 h) enhances NHEJ usage but reduces homologous recombination (HR) in cells.
PFM03 is a MRE11 Endonuclease inhibitor. PFM03 regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ).
体外研究：
PFM03 (50-400 μM; 30 min) specifically inhibits MRE11 endonuclease activity.PFM03 (100 μM; 30 min) causes normal DSB repair in G2 (CENPF+) cells.PFM03 (50 μM; 8 h) enhances NHEJ usage but reduces homologous recombination (HR) in cells.
产品资料
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