产品
编 号：F745760
分子式：C152H222N38O50
分子量：3381.62
分子式：C152H222N38O50
分子量：3381.62
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CAS No: 1544300-84-6
产品详情
生物活性：
Dasiglucagon is a human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research.
体内研究：
Dasiglucagon 的 PK 图谱显示血浆水平的剂量依赖性和快速升高。 Dasiglucagon dose
0.1 mg0.3 mg 0.6 mg 1.0 mg
N5161616
AUC0–30min (pmol*h/L)99.4 (32.0)302 (78.9)444 (163)884 (307)
AUC0–360min (pmol*h/L)451 (123)1360 (166)1630 (368)4800 (697)
AUC0–inf (pmol*h/L)451 (123)1360 (166)2640 (365)4810 (696)
Cmax (pmol/L)334 (113)976 (208)1570 (445)2800 (767)
tmax (h)0.50 (0.5-0.6)0.63 (0.3-0.8)0.58 (0.5-1.7)0.63 (0.3-0.8)
t1/2 (h)0.43 (0.07)0.43 (0.07)0.49 (0.14)0.54 (0.17)
Dasiglucagon is a human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research.
体内研究：
Dasiglucagon 的 PK 图谱显示血浆水平的剂量依赖性和快速升高。 Dasiglucagon dose
0.1 mg0.3 mg 0.6 mg 1.0 mg
N5161616
AUC0–30min (pmol*h/L)99.4 (32.0)302 (78.9)444 (163)884 (307)
AUC0–360min (pmol*h/L)451 (123)1360 (166)1630 (368)4800 (697)
AUC0–inf (pmol*h/L)451 (123)1360 (166)2640 (365)4810 (696)
Cmax (pmol/L)334 (113)976 (208)1570 (445)2800 (767)
tmax (h)0.50 (0.5-0.6)0.63 (0.3-0.8)0.58 (0.5-1.7)0.63 (0.3-0.8)
t1/2 (h)0.43 (0.07)0.43 (0.07)0.49 (0.14)0.54 (0.17)
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