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编 号:F745721
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CAS No: 1535963-91-7
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Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research.
体内研究:
Satralizumab (120 mg, Subcutaneously, once every 2 weeks, for 4 weeks) prevents dTAA formation and progression in rattus norvegicus.Animal Model:Rattus norvegicus (forty, male, 10-week-old, four equal groups)
Dosage:120 mg
Administration:Subcutaneously, once every 2 weeks, for 4 weeks
Result:Prevented dTAA (descending thoracic aorta aneurysm) formation and progression.