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编 号:F745707
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结构图
CAS No: 1531594-08-7
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生物活性:
Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex.
体外研究:
Tesidolumab (LFG316) possesses a half-life in humans of approximately 9 days.Tesidolumab (LFG316) binds to a distinct epitope to that of eculizumab and ravulizumab, distant to Arg 885.