产品
编 号：F745497
分子式：C20H37N3O5
分子量：399.52
分子式：C20H37N3O5
分子量：399.52
产品类型
规格
价格
是否有货
结构图
CAS No: 148333-42-0
产品详情
生物活性：
Ac-Leu-Leu-Norleucinol (ALLN) is a calpain inhibitor, can be used for research of Acetaminophen (HY-66005) induced acute liver damage, and lowers glutamic-oxalacetic transaminease (ALT) and glutamic-pyruvic transaminase (AST).
体内研究：
Ac-Leu-Leu-Norleucinol (10 mg/kg, 20 mg/kg; i.p.; single dose) effectively prevents Acetaminophen (HY-66005)-induced acute liver injury in mice model.Animal Model:Acute liver injury model induced by Acetaminophen (APAP) in C57BL/6 mice (18-22 g)
Dosage:10 mg/kg, 20 mg/kg; accompanied with 300 mg/kg APAP (i.p.)
Administration:Intraperitoneal injection; collected tissue samples 24 hr after
Result:Significantly reduced APAP-induced stem cell necrosis and lowered the level of glutamic-oxalacetic transaminease (ALT) and glutamic-pyruvic transaminase (AST).Injection alone did not cause pathological changes in the liver.
Ac-Leu-Leu-Norleucinol (ALLN) is a calpain inhibitor, can be used for research of Acetaminophen (HY-66005) induced acute liver damage, and lowers glutamic-oxalacetic transaminease (ALT) and glutamic-pyruvic transaminase (AST).
体内研究：
Ac-Leu-Leu-Norleucinol (10 mg/kg, 20 mg/kg; i.p.; single dose) effectively prevents Acetaminophen (HY-66005)-induced acute liver injury in mice model.Animal Model:Acute liver injury model induced by Acetaminophen (APAP) in C57BL/6 mice (18-22 g)
Dosage:10 mg/kg, 20 mg/kg; accompanied with 300 mg/kg APAP (i.p.)
Administration:Intraperitoneal injection; collected tissue samples 24 hr after
Result:Significantly reduced APAP-induced stem cell necrosis and lowered the level of glutamic-oxalacetic transaminease (ALT) and glutamic-pyruvic transaminase (AST).Injection alone did not cause pathological changes in the liver.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备