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编 号:F745188
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CAS No: 1438851-35-4
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生物活性:
ABP 215 (Bevacizumab-awwb), a Bevacizumab (Bevacizumab (HY-P9906)) biosimilar, is a humanized IgG1 monoclonal antibody targeting VEGFA (VEGFR). ABP 215 has anticancer effects, and can be used metastatic colorectal cancer (mCRC) research.
体外研究:
ABP 215 (Bevacizumab-awwb) 与 VEGF-A 结合,阻止 VEGF-A 与内皮细胞表面的 VEGF 受体结合,抑制内皮细胞增殖和新血管形成,从而导致肿瘤脉管系统正常化。