产品
编 号:F745114
分子式:C22H22N4O3
分子量:390.44
产品类型
结构图
CAS No: 1429509-82-9
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产品详情
生物活性:
Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 (PDE9) inhibitor. Irsenontrine can be used for the research of neurological diseases.
体内研究:
Irsenontrine (0.3, 3.3 mg/kg; p.o.) exhibits a significant ameliorative effect on the percentage of exploration of the novel object at 3.3 mg/kg in Scopolamine-induced rats.Irsenontrine (1 mg/kg; p.o.) and memantine hydrochloride (1 mg/kg; p.o.) combined treatment group exhibits a significantly higher percentage of exploration of the novel object than memantine hydrochloride (1 mg/kg) alone.
体外研究:
Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 (PDE 9) inhibitor.