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编 号:F745047
分子式:C8H11N6NaO5S
分子量:326.26
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CAS No: 1426572-65-7
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生物活性:
Antibacterial agent 58, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime.
体外研究:
Antibacterial agent 58 (example 23) significantly lowers MIC value of Ceftazidime (MIC=1, 2, 8 mcg/ml for E. coli NCTC 1335 1, E. coli M50, and E. coli 7MP, respectively). Antibacterial agent 58 significantly lowers MIC values of the antibacterial agent Ceftazidime (MIC=0.2~2 mcg/ml for class A ESBL; 2-8 mcg/ml for class C ESBL; 4-8 mcg/ml for KPC ESBL). From WO2013030735A1, example 23.Class A ESBL: E.coli W 13353; E.coli W3351; E.coli W 13352Class C ESBL: E.coli M 50; E.coli 7 MIP; E.coli B 89KPC ESBL: K.pneumoniae H 520; K.pneumoniae H 521; K. pneumoniae H 522Class D ESBL: A.Baumannii13301; A.baumannii 13304