产品
编 号:F744993
分子式:C19H22N6OS
分子量:382.48
产品类型
结构图
CAS No: 1424371-93-6
联系客服
产品详情
生物活性:
MK-8189 is a potent, orally active and selective PDE10A inhibitor with a Ki value of 29 pM. MK-8189 can be used in research of schizophrenia.
体内研究:
MK-8189 (0.25-0.75 mg/kg; po) 以剂量依赖的方式减弱大鼠的运动活动。Animal Model:Male Wistar-Hannover rats
Dosage:0.25, 0.5, and 0.75 mg/kg
Administration:Oral administration
Result:Improved identification ability relative to the vector handling animal.