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编 号:F744993
分子式:C19H22N6OS
分子量:382.48
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1mg
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5mg
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10mg
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生物活性:
MK-8189 is a potent, orally active and selective PDE10A inhibitor with a Ki value of 29 pM. MK-8189 can be used in research of schizophrenia.

体内研究:
MK-8189 (0.25-0.75 mg/kg; po) 以剂量依赖的方式减弱大鼠的运动活动。Animal Model:Male Wistar-Hannover rats
Dosage:0.25, 0.5, and 0.75 mg/kg
Administration:Oral administration
Result:Improved identification ability relative to the vector handling animal.
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