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编 号:F744903
分子式:C24H41N3
分子量:371.6
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5mg
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10mg
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25mg
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50mg
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Dynole 2?24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2?24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC??(CME)=1.9 μM). Dynole 2?24 also shows 4.4-fold selectivity for dynamin I. Dynole 2?24 is active in-cell inhibitor of clathrin-mediated endocytosis. CME: Clathrin mediated endocytosis
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