产品
编 号:F744742
分子式:C20H17FN8O2
分子量:420.4
产品类型
结构图
CAS No: 1397683-26-9
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生物活性:
BACE1-IN-13 (Compound 36) is an orally active BACE1 inhibitor with an IC50 value of 2.9 nM. BACE1-IN-13 is highly potent in hAβ42 cell (IC50 = 1.3 nM). BACE1-IN-13 has cardiovascularly safty and elicits sustained Aβ42 reduction in mouse and dog animal models.