产品
编 号:F744634
分子式:C30H31Cl2N7O4
分子量:624.52
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1mg
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询价
5mg
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生物活性:
DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. DYRKs-IN-1 hydrochloride has antitumor activity.

体外研究:
DYRKs-IN-1 hydrochloride (compound 30) increases the cellular potency against the human colon tumor cell line SW 620 with an EC50 of 27 nM. DYRKs-IN-1 hydrochloride (Example 183) is a potent DYRKs inhibitor.
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