产品
编 号：F744233
分子式：C15H11ClF2N2O3S
分子量：372.77
分子式：C15H11ClF2N2O3S
分子量：372.77
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CAS No: 1346113-84-5
产品详情
生物活性：
PKM2 activator 3 is a potent PKM2 activator with an AC50 value of 90 nM. PKM2 activator 3 has good Caco-2 permeability, a low efflux ratio and high microsomal stability. PKM2 activator 3 can be used for researching anticancer.(AC50:?the concentration which gives 50% activation of enzyme.)
体内研究：
PKM2 activator 3 (compound 66) has good Caco-2 permeability, a low efflux ratio (0.84) and high microsomal stability (t1/2 = 277.2 min in human liver microsomes and 117.5 min in mouse liver microsomes).
PKM2 activator 3 is a potent PKM2 activator with an AC50 value of 90 nM. PKM2 activator 3 has good Caco-2 permeability, a low efflux ratio and high microsomal stability. PKM2 activator 3 can be used for researching anticancer.(AC50:?the concentration which gives 50% activation of enzyme.)
体内研究：
PKM2 activator 3 (compound 66) has good Caco-2 permeability, a low efflux ratio (0.84) and high microsomal stability (t1/2 = 277.2 min in human liver microsomes and 117.5 min in mouse liver microsomes).
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