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编 号:F744046
分子式:C68H54O43
分子量:1559.13
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生物活性:
Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum.

体外研究:
Trypanothione synthetase-IN-3 (30 min) displays noncompetitive inhibitory behavior against Li TryS with IC50 values of 2 μM -5.6 μM (determined by various substrates).Trypanothione synthetase-IN-3 (24 h) inhibits proliferation of L. infantum axenic amastigotes with an EC50 value of 43.7 μM.
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