产品
编 号：F073618
分子式：NH4Cl
分子量：53.49
分子式：NH4Cl
分子量：53.49
产品类型
规格
价格
是否有货
250mg
280
In-stock
结构图
CAS No: 12125-02-9
产品详情
生物活性：
Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.
体内研究：
Ammonium chloride (0.28 M in drinking water) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy.Animal Model:8-9-week-old C57B/L6 mice
Dosage:0.28 M in drinking water (5 mg/kg doxorubicin once a week for 2 weeks)
Administration:0.28 M in drinking water (5 mg/kg doxorubicin once a week for 2 weeks)
Result:Effectively improved doxorubicin (DOX)-induced cardiomyocyte apoptosis and cardiac dysfunction in mice.
体外研究：
Ammonium chloride (NH4Cl), a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells.
Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.
体内研究：
Ammonium chloride (0.28 M in drinking water) promotes the survival of myocardial cells in vivo by decreasing contractile dysfunction, cardiac hypertrophy, inflammation, apoptosis and autophagy.Animal Model:8-9-week-old C57B/L6 mice
Dosage:0.28 M in drinking water (5 mg/kg doxorubicin once a week for 2 weeks)
Administration:0.28 M in drinking water (5 mg/kg doxorubicin once a week for 2 weeks)
Result:Effectively improved doxorubicin (DOX)-induced cardiomyocyte apoptosis and cardiac dysfunction in mice.
体外研究：
Ammonium chloride (NH4Cl), a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells.
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