产品
编 号:F009094
分子式:C25H23Cl2N5O3
分子量:512.39
产品类型
结构图
CAS No: 1018674-83-3
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产品详情
生物活性:
CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer.
体外研究:
CVT-11127 (1 μM, 48 h) shows antiproliferation activity in H460 cells.CVT-11127 (1 μM, 48 h) decreases the the population of cells in S-phase by 75%.CVT-11127 (1 μM, 48 h) induces apoposis in H460 cells.CVT-11127 (1, 2 μM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells.