产品
编 号:F743841
分子式:C203H330N62O54S
分子量:4535.24
产品类型
结构图
CAS No: 129405-61-4
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产品详情
生物活性:
PACAP (1-38) free acid is an endogenous neuropeptide. PACAP (1-38) free acid potently stimulates antral motility and somatostatin secretion, inhibits the secretion of gastrin and stimulates the release of vasoactive intestinal polypeptide, gastrin releasing peptide and substance P. PACAP (1-38) free acid also enhances N-methyl-D-aspartate receptor function and expression of brain-derived neurotrophic factor through RACK1.
体外研究:
PACAP (1-38) free acid (1 nM) 增加 P 物质、胃泌素释放肽和血管活性肠肽的释放。PACAP (1-38) free acid (100 nM; 10 min) 诱导大鼠海马切片中 NR2B 的酪氨酸磷酸化。