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编 号：F743783
分子式：C28H34O8
分子量：498.56
分子式：C28H34O8
分子量：498.56
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CAS No: 1281766-66-2
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生物活性：
6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research.
体外研究：
6-Acetylnimbandiol (10, 30, 100 μM; 48 h) shows antimelanogenic activity in B16 melanoma cells.6-Acetylnimbandiol (50, 100 μM; 48 h) exerts melanogenesis inhibition by inhibiting expression of MITF, tyrosinase, TRP-1, and TRP-2 in B16 melanoma cells.
6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research.
体外研究：
6-Acetylnimbandiol (10, 30, 100 μM; 48 h) shows antimelanogenic activity in B16 melanoma cells.6-Acetylnimbandiol (50, 100 μM; 48 h) exerts melanogenesis inhibition by inhibiting expression of MITF, tyrosinase, TRP-1, and TRP-2 in B16 melanoma cells.
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