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编 号：F743689
分子式：C17H16N4O
分子量：292.34
分子式：C17H16N4O
分子量：292.34
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CAS No: 1263820-18-3
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生物活性：
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn2+ in living cells.
体外研究：
After incubation with PMQA (20 μM) for 1 h, weak green fluorescence appeared, presumably caused by the probe capturing intracellular zinc from its native ligands since PMQA has high affinity for zinc.The response of PMQA to Zn2+ can be reversed by N,N,N’,N’-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) or EDTA.When the stock solution of PMQA (0.1 mM in Tris Buffer) is kept at room temperature for a week, there is no significant loss of PMQA determined by HPLC analysis.
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn2+ in living cells.
体外研究：
After incubation with PMQA (20 μM) for 1 h, weak green fluorescence appeared, presumably caused by the probe capturing intracellular zinc from its native ligands since PMQA has high affinity for zinc.The response of PMQA to Zn2+ can be reversed by N,N,N’,N’-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) or EDTA.When the stock solution of PMQA (0.1 mM in Tris Buffer) is kept at room temperature for a week, there is no significant loss of PMQA determined by HPLC analysis.
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