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编 号:F072301
分子式:C22H21F2NO4S
分子量:433.47
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L-670596 is an orally active and selective thrombsxane A2 receptor/prostaglandin receptor antagonist. L-670596 inhibits arachidonic acid (HY-109590) and U-44069 induced bronchoconstriction in the guinea pig. L-670596 also inhibits the aggregation of human platelet rich plasma induced by U-44069.

体内研究:
L-670596 (0.03 mg/kg ; i.v.; single) 抑制豚鼠中花生四烯酸和 U-44069 诱导的支气管收缩。L-670596 (2 mg/kg; i.v.; single) 抑制猪的血小板聚集成胶原蛋白。Animal Model:Guinea pig (arachidonic acid and U-44069 induced bronchoconstriction model).
Dosage:0.03mg/kg
Administration:Intravenous injection; single.
Result:Inhibited arachidonic acid and U-44069 induced bronchoconstriction.

体外研究:
L-670596 抑制 U-44069 诱导的人类富血小板血浆的聚集。
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