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编 号:F743177
分子式:C25H25F2NO3
分子量:425.47
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Antimalarial agent 11 (compound 1), a spirocyclic chromane, is a potent antimalarial agent. Antimalarial agent 11 exhibits excellent potency with an EC50 of 350 nM against the Chloroquine-resistant Dd2 strain. Antimalarial agent 11 has EC50s?of 1.48?μM and 1.81?μM against D6 and ARC08-022 strains, respectively.
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