产品
编 号：F071934
分子式：C6H6Cl2N2O4S2
分子量：305.16
分子式：C6H6Cl2N2O4S2
分子量：305.16
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
200
In-stock
10mg
320
In-stock
50mg
960
In-stock
结构图
CAS No: 120-97-8
产品详情
生物活性：
Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research.
体内研究：
Dichlorphenamide can reduce IOP locally in male albino rabbits.Animal Model:Male albino rabbits (approximately 2.5 kg)
Dosage:50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg
Administration:Eye drop of 50 μL or Oral gavage of 2 mg/kg or 6 mg/kg, 5 hours
Result:Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration, and demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research.
体内研究：
Dichlorphenamide can reduce IOP locally in male albino rabbits.Animal Model:Male albino rabbits (approximately 2.5 kg)
Dosage:50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg
Administration:Eye drop of 50 μL or Oral gavage of 2 mg/kg or 6 mg/kg, 5 hours
Result:Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration, and demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
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