产品
编 号：F743162
分子式：C19H20N6O4
分子量：396.4
分子式：C19H20N6O4
分子量：396.4
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CAS No: 1212663-24-5
产品详情
生物活性：
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 μM, 4.21 μM and 14.2 μM, respectively.
体外研究：
Only CBK289001 inhibits TRAP3high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 μM or 100 μM. CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells.
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 μM, 4.21 μM and 14.2 μM, respectively.
体外研究：
Only CBK289001 inhibits TRAP3high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 μM or 100 μM. CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells.
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