产品
编 号：F742967
分子式：C72H116N20O19
分子量：1565.81
分子式：C72H116N20O19
分子量：1565.81
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CAS No: 1187852-48-7
产品详情
生物活性：
SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity.
体内研究：
SOR-C13 (腹腔给药; 400, 600, 800 mg/kg; 每天; 第 1 至 12 天) 可有效抑制雌性 NOD/SCID 小鼠 SKOV-3 细胞肿瘤的生长。 Animal Model:Female NOD/SCID mice with SKOV-3 cell
Dosage:400,600, 800 mg/kg
Administration:IP; daily; on days 1 to 12
Result:Effectively inhibited the growth of tumor.
SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity.
体内研究：
SOR-C13 (腹腔给药; 400, 600, 800 mg/kg; 每天; 第 1 至 12 天) 可有效抑制雌性 NOD/SCID 小鼠 SKOV-3 细胞肿瘤的生长。 Animal Model:Female NOD/SCID mice with SKOV-3 cell
Dosage:400,600, 800 mg/kg
Administration:IP; daily; on days 1 to 12
Result:Effectively inhibited the growth of tumor.
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