产品
编 号：F742949
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1186098-83-8
产品详情
生物活性：
Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma.
体内研究：
Oxelumab (5 和 30 mg/kg；腹腔注射，每天一次，共两次) 影响 IL-6 的浓度和脾人效应记忆 T 细胞和开关 B 细胞的频率。Animal Model:NSG mice with PBMCs from UC patients with simple clinical colitis activity index (SCCAI)
Dosage:5 and 30 mg/kg
Administration:Intraperitoneal injectionon; 5 and 30 mg/kg, once daily, on days 6 and 13
Result:Reversed the ethanol-induced colon dilated and the lost of distinct pattern of pellets. Decreased the level of IL-6 and increased the concentrations of glutamic acid. Reduced frequencies of splenic human effector memory T cells and switched B cells.
体外研究：
Oxelumab (10 μg/mL；3 天) 抑制 NK 细胞的增殖.
Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma.
体内研究：
Oxelumab (5 和 30 mg/kg；腹腔注射，每天一次，共两次) 影响 IL-6 的浓度和脾人效应记忆 T 细胞和开关 B 细胞的频率。Animal Model:NSG mice with PBMCs from UC patients with simple clinical colitis activity index (SCCAI)
Dosage:5 and 30 mg/kg
Administration:Intraperitoneal injectionon; 5 and 30 mg/kg, once daily, on days 6 and 13
Result:Reversed the ethanol-induced colon dilated and the lost of distinct pattern of pellets. Decreased the level of IL-6 and increased the concentrations of glutamic acid. Reduced frequencies of splenic human effector memory T cells and switched B cells.
体外研究：
Oxelumab (10 μg/mL；3 天) 抑制 NK 细胞的增殖.
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