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编 号:F742827
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结构图
CAS No: 1169766-01-1
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生物活性:
Ramatercept is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy.
体内研究:
Ramatercept (10 mg/kg;皮下注射;每周 3 次,持续 5 周) 显著增加了小鼠的肌肉量。