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编 号：F742824
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1mg
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CAS No: 1167985-17-2
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生物活性：
Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis.
体内研究：
Ozoralizumab (ATN-103; 1 mg/kg; s.c.; Tg197 人 TNF 转基因小鼠) 抑制关节炎并降低关节炎评分。Animal Model:Tg197 human TNF transgenic mice
Dosage:1 mg/kg
Administration:Subcutaneous injection
Result:Reduced the mean histopathologic score in the Tg197 mice.Had ability to neutralize TNFα activity.
体外研究：
Ozoralizumab (ATN-103; 0-1000 pM; 48 h) 在 L929 细胞细胞毒性试验中具有高 TNFα 中和效力，对人 TNFα 和猴 TNFα 的 KD 值分别为 20.2 pM 和 16.1 pM。
Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis.
体内研究：
Ozoralizumab (ATN-103; 1 mg/kg; s.c.; Tg197 人 TNF 转基因小鼠) 抑制关节炎并降低关节炎评分。Animal Model:Tg197 human TNF transgenic mice
Dosage:1 mg/kg
Administration:Subcutaneous injection
Result:Reduced the mean histopathologic score in the Tg197 mice.Had ability to neutralize TNFα activity.
体外研究：
Ozoralizumab (ATN-103; 0-1000 pM; 48 h) 在 L929 细胞细胞毒性试验中具有高 TNFα 中和效力，对人 TNFα 和猴 TNFα 的 KD 值分别为 20.2 pM 和 16.1 pM。
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