产品
编 号：F071476
分子式：C22H14F3NO3
分子量：397.35
分子式：C22H14F3NO3
分子量：397.35
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 1208222-39-2
产品详情
生物活性：
VU 0365114 is a selective mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM, and >30 μM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human β-cells.
体外研究：
VU 0365114 (10 μM) increases insulin secretion stimulated by ACh in human β-cells.VU 0365114 (10 μM) does not alter somatostatin secretion stimulated by ACh in human β-cells.
VU 0365114 is a selective mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM, and >30 μM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human β-cells.
体外研究：
VU 0365114 (10 μM) increases insulin secretion stimulated by ACh in human β-cells.VU 0365114 (10 μM) does not alter somatostatin secretion stimulated by ACh in human β-cells.
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