产品
编 号：F742666
分子式：C31H45FN4O10
分子量：652.71
分子式：C31H45FN4O10
分子量：652.71
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1135688-25-3
产品详情
生物活性：
Z-LEVD-FMK is a cell-permeable caspase-4 inhibitor. Z-LEVD-FMK blocks ER stress-induced apoptosis in cancer cells.
体外研究：
Z-LEVD-FMK (2 ng/mL, 30 min) blocks IL-1β-induced IL-8 production in hRPE cells.Z-LEVD-FMK (2 μM) inhibits caspase-3 activity in hRPE cells.Z-LEVD-FMK (20 μM, 96 h) completely blocks E2-induced PARP cleavage in 5C cells.Z-LEVD-FMK (20 μM, 96 h) reverses E2-inhibited growth and prevents morphologic alterations associated with apoptosis in 5C cells.
Z-LEVD-FMK is a cell-permeable caspase-4 inhibitor. Z-LEVD-FMK blocks ER stress-induced apoptosis in cancer cells.
体外研究：
Z-LEVD-FMK (2 ng/mL, 30 min) blocks IL-1β-induced IL-8 production in hRPE cells.Z-LEVD-FMK (2 μM) inhibits caspase-3 activity in hRPE cells.Z-LEVD-FMK (20 μM, 96 h) completely blocks E2-induced PARP cleavage in 5C cells.Z-LEVD-FMK (20 μM, 96 h) reverses E2-inhibited growth and prevents morphologic alterations associated with apoptosis in 5C cells.
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