产品
编 号：F742264
分子式：C20H19N3O4
分子量：365.38
分子式：C20H19N3O4
分子量：365.38
产品类型
规格
价格
是否有货
结构图
CAS No: 1050587-57-9
产品详情
生物活性：
Z164597606 is a selective BChE inhibitor (IC50: 1.3 and 1.7 μM for eqBChE and hBChE). Z164597606 forms a π-π stacking interaction with the amino acid Trp82 of hBChE. Z164597606 can be used for the research of Alzheimer’s disease (AD).
体外研究：
Z164597606 (10 μM) potently inhibits BChE activity, with no more than 30% inhibitory against ACHE.Z164597606 (0.5-20 μM) may bind to catalytic “anionic” site (CAS) when interacting with BChE (determined by Lineweaver-Burk reciprocal plots).Z164597606 (10 and 50 μM) shows no toxicity on neuronal cell line SH-SY5Y.
Z164597606 is a selective BChE inhibitor (IC50: 1.3 and 1.7 μM for eqBChE and hBChE). Z164597606 forms a π-π stacking interaction with the amino acid Trp82 of hBChE. Z164597606 can be used for the research of Alzheimer’s disease (AD).
体外研究：
Z164597606 (10 μM) potently inhibits BChE activity, with no more than 30% inhibitory against ACHE.Z164597606 (0.5-20 μM) may bind to catalytic “anionic” site (CAS) when interacting with BChE (determined by Lineweaver-Burk reciprocal plots).Z164597606 (10 and 50 μM) shows no toxicity on neuronal cell line SH-SY5Y.
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