产品
编 号:F742193
分子式:C32H48O5
分子量:512.72
产品类型
结构图
CAS No: 103963-38-8
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产品详情
生物活性:
Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway.
体外研究:
Ganoderic acid S (0, 39.1, 97.7 μM; 12 h) 在 HeLa 细胞中导致细胞周期停滞在 S 期。Ganoderic acid S 剂量依赖性地导致线粒体膜电位的崩溃。Ganoderic acid S 诱导细胞色素 c 从线粒体大量释放到 HeLa 细胞的胞质溶胶中。