产品
编 号:F742145
分子式:C118H193N33O32
分子量:2586
产品类型
结构图
CAS No: 103238-06-8
联系客服
产品详情
生物活性:
CPF-7 (Caerulein precursor fragment) is an insulin-releasing peptide that stimulates the release of insulin. CPF-7 can induce epithelial-mesenchymal transition by upregulating Snai1 expression in PANC-1 ductal cells. CPF-7 also induces exocrine plasticity by upregulating Ngn3 expression. CPF-7 can be used in the research of type 2 diabetes.
体外研究:
CPF-7 (50 nM; 7 days) 将 PANC-1 外分泌细胞转化为胰腺内分泌前体细胞。CPF-7 (3 μM; 20 min) 刺激 BRIN-BD11 大鼠克隆 β 细胞系中的胰岛素释放。