产品
编 号:F742088
分子式:C58H79N15O15
分子量:1226.34
产品类型
结构图
CAS No: 102634-23-1
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产品详情
生物活性:
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models.
体内研究:
Lamprey LH-RH I (5-200 μg/kg; i.p.; single dose or twice) elevates plasma steroid levels and stimulates lamprey ovulation.Animal Model:Female sea-run sea lampreys
Dosage:5 μg/kg, 50 μg/kg, 100 μg/kg, 200 μg/kg; dissolved in 0.6% NaCl in distilled water
Administration:Intraperitoneal injection; single dose or twice; observed for 30 days
Result:Significantly increased estradiol in a dose-related manner.Resulted 80% of the lampreys ovulation at 200 or 100 μg/kg compared in a doserelated manner.
体外研究:
Lamprey LH-RH I has a primary mechanism of transport to the pituitary is simple diffusion from neuronal terminals in the neurohypophysis to the adenohypophysis. An additional route is via secretion into the third ventricle and transport by tanycytes to the adenohypophysis.