产品
编 号:F741923
分子式:C23H22N2O3
分子量:374.43
产品类型
结构图
CAS No: 1005178-02-8
联系客服
产品详情
生物活性:
TI17 is an inhibitor of the thyroid hormone receptor-interacting protein Trip13 and has anticancer activity. TI17 effectively inhibits multiple myeloma (MM) cell proliferation and induces cell cycle arrest and apoptosis. Trip13 is an AAA-ATPase that mediates double-strand break (DSB) repair; TI17 inhibits Trip13 function and increases DNA damage.