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编 号:F741873
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CAS No: 1000676-41-4
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生物活性:
Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research.
体内研究:
Lirilumab (intravenous injection; 15 mg/kg; once) treatment enhances survival rate of mice injected with tumor.Animal Model:Rag1KO-Tg KIR mice injected with tumor cells
Dosage:15 mg/kg
Administration:intravenous injection; 15 mg/kg; once
Result:Showed 6 of 7 mice survival over a 100-day period, whereas untreated or IC-treated mice all died.