产品
编 号：F741839
分子式：C23H25NO4S
分子量：411.51
分子式：C23H25NO4S
分子量：411.51
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 2883495-35-8
产品详情
生物活性：
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 μM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces Apoptosis.
体外研究：
Enpp/Carbonic anhydrase-IN-1 (compound 1e) (0-100 μM; ) inhibits some cancer cells growth with IC50s of 0.32, 0.40, 0.58, 0.87, 0.40, 0.96 μM for K-562, RPMI-8226, SR, COLO 205, HT-29, SF-539 cells, respectively.Enpp/Carbonic anhydrase-IN-1 (0-2 μM) shows low cytotoxic against normal breast epithelial cells (HME1) and normal skin fibroblast cells (F180) with IC50s of > 50 μM.Enpp/Carbonic anhydrase-IN-1 (0.32, 0.64 μM) induces apoptosis in a dose-dependent manner at K-562 cells.
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 μM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces Apoptosis.
体外研究：
Enpp/Carbonic anhydrase-IN-1 (compound 1e) (0-100 μM; ) inhibits some cancer cells growth with IC50s of 0.32, 0.40, 0.58, 0.87, 0.40, 0.96 μM for K-562, RPMI-8226, SR, COLO 205, HT-29, SF-539 cells, respectively.Enpp/Carbonic anhydrase-IN-1 (0-2 μM) shows low cytotoxic against normal breast epithelial cells (HME1) and normal skin fibroblast cells (F180) with IC50s of > 50 μM.Enpp/Carbonic anhydrase-IN-1 (0.32, 0.64 μM) induces apoptosis in a dose-dependent manner at K-562 cells.
产品资料
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