产品
编 号:F741835
分子式:C22H31NO2
分子量:341.49
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.

体外研究:
CB2R/FAAH modulator-3 (compound 27)(10 μM) 在未刺激的单核细胞和巨噬细胞中,可以降低促炎细胞因子 TNFα、IFN-γ、IL-1β 和 IL6 的产生。
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