产品
编 号:F741834
分子式:C31H31ClF3N9O5
分子量:702.08
产品类型
结构图
CAS No: 2869954-34-5
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产品详情
生物活性:
HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research.
体外研究:
HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42) has an IC50 value of 100 nM for WRN ATPase and GI50 values of 50 nM and >10 μM for SW48 and DLD1 WRN-KO cell lines, respectively.