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编 号:F741822
分子式:C16H15ClN2O
分子量:286.76
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生物活性:
PBRM1-BD2-IN-7 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with an IC50 value of 0.29 μM. PBRM1-BD2-IN-7 can be used for the research of cancer.

体外研究:
PBRM1-BD2-IN-7 (0, 0.1, 1, and 10 μM; 5 days) selectively inhibit growth of a PBRM1-dependent prostate cancer cell line.PBRM1-BD2-IN-7 has inhibitory activity for PBRM1-BD2 with IC50 value of 0.29 μM.
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