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编 号:F741780
分子式:C30H38N8O4
分子量:574.67
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
CSF1R-IN-3 (compound 21) is a potent and orally active CSF-1R inhibitor (IC50=2.1 nM). CSF1R-IN-3 is a potent antiproliferative activity against colorectal cancer cells. CSF1R-IN-3 inhibits the progression of colorectal cancer by suppressing the migration of macrophages, reprograming M2-like macrophages to the M1 phenotype, and enhancing the antitumor immunity.
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