产品
编 号：F741720
分子式：C15H22ClN5O4S
分子量：403.88
分子式：C15H22ClN5O4S
分子量：403.88
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 2687222-59-7
产品详情
生物活性：
Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity.
体内研究：
Enpp-1-IN-14 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth.Animal Model:Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells)
Dosage:50 mg/kg
Administration:IP; BID, for 31 days (given a single 10 Gy exposure of focal radiation to the tumor site)
Result:Significantly inhibited tumor growth.
Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. Enpp-1-IN-14 has anti-tumor activity.
体内研究：
Enpp-1-IN-14 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth.Animal Model:Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells)
Dosage:50 mg/kg
Administration:IP; BID, for 31 days (given a single 10 Gy exposure of focal radiation to the tumor site)
Result:Significantly inhibited tumor growth.
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