产品
编 号：F741656
分子式：C12H18FNO3S.1/2C4H6O6
分子量：350.39
分子式：C12H18FNO3S.1/2C4H6O6
分子量：350.39
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规格
价格
是否有货
5mg
询价
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10mg
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50mg
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100mg
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结构图
CAS No: 2562346-14-7
产品详情
生物活性：
Mesdopetam (IRL790) hemitartrate is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in Parkinson disease.
体内研究：
Mesdopetam (IRL790) (3.7, 11, 33, or 100 μmol/kg; s.c.) hemitartrate dose-dependently inhibits the behavioral activation following pretreatment with D-amphetamine or MK-80.Animal Model:Male Sprague-Dawley rats
Dosage:3.7, 11, 33, or 100 μmol/kg (synthesized in-house as HCl salt, was dissolved in physiologic saline (0.9% w/v NaCl)
Administration:s.c. was administered subcutaneously 4 min before the start of recording
Result:Dose-dependently inhibited the behavioral activation following pretreatment with D-amphetamine or MK-801.
Mesdopetam (IRL790) hemitartrate is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate is used for the research of motor and psychiatric complications in Parkinson disease.
体内研究：
Mesdopetam (IRL790) (3.7, 11, 33, or 100 μmol/kg; s.c.) hemitartrate dose-dependently inhibits the behavioral activation following pretreatment with D-amphetamine or MK-80.Animal Model:Male Sprague-Dawley rats
Dosage:3.7, 11, 33, or 100 μmol/kg (synthesized in-house as HCl salt, was dissolved in physiologic saline (0.9% w/v NaCl)
Administration:s.c. was administered subcutaneously 4 min before the start of recording
Result:Dose-dependently inhibited the behavioral activation following pretreatment with D-amphetamine or MK-801.
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