产品
编 号:F741641
分子式:C18H14Cl2F2N4O2S
分子量:459.3
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1mg
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5mg
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生物活性:
BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2

体内研究:
BR102910 (C57BL/6J mice, 0-30 mg/kg, Orally, once) shows significant FAP inhibition in a dose dependent manner.Animal Model:C57BL/6J mice (n = 5 per group)
Dosage:0, 10 and 30 mg/kg
Administration:Orally, once
Result:Showed significant FAP inhibition in a dose dependent manner.
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