产品
编 号:F741600
分子式:C21H14F3N3O
分子量:381.35
产品类型
结构图
CAS No: 2446880-46-0
联系客服
产品详情
生物活性:
ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study.
体外研究:
ND-011992 对牛心脏线粒体膜 NADH 氧化酶活性有抑制作用,IC50 为 3.27 μM。