产品
编 号:F741596
分子式:C26H33Cl2N3O3
分子量:506.46
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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100mg
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生物活性:
BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 hydrochloride impairs the anchorage-independent growth of KEAP1-mutant cancer cells.

体外研究:
BPK-29 hydrochloride substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers.
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