产品
编 号：F741585
分子式：C32H35N7O2
分子量：549.67
分子式：C32H35N7O2
分子量：549.67
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2421141-40-2
产品详情
生物活性：
GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases.
体内研究：
Summary of the pharmacokinetic parameters of GLUT inhibitor-1 (compound 15b; 30 mg/kg) in mouse and rat.ParameterMouseRat
oral Cmax (ng/mL)25251675
oral AUC (ng/mL)58906813
CL (mL/min/kg)4037
Vdss (L/Kg)1.70 4.51
t1/2 (h)0.7852.59
F (%)45.449.4
B/Pb0.05
b: Solubility is determined in PBS buffer solutions.
GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases.
体内研究：
Summary of the pharmacokinetic parameters of GLUT inhibitor-1 (compound 15b; 30 mg/kg) in mouse and rat.ParameterMouseRat
oral Cmax (ng/mL)25251675
oral AUC (ng/mL)58906813
CL (mL/min/kg)4037
Vdss (L/Kg)1.70 4.51
t1/2 (h)0.7852.59
F (%)45.449.4
B/Pb0.05
b: Solubility is determined in PBS buffer solutions.
产品资料
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