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编 号:F741509
分子式:C21H21FN6O3
分子量:424.43
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer.

体内研究:
Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice.

体外研究:
Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells.
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