产品
编 号:F741509
分子式:C21H21FN6O3
分子量:424.43
产品类型
结构图
CAS No: 2359649-81-1
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产品详情
生物活性:
Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer.
体内研究:
Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice.
体外研究:
Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells.