产品
编 号：F741484
分子式：C17H11F6NO3
分子量：391.26
分子式：C17H11F6NO3
分子量：391.26
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 2279077-93-7
产品详情
生物活性：
SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 μM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression.
体外研究：
SRD5A1-IN-1 (Compound 4) (0.5-2.5 μM; 24 h) 降低 SRD5A1 蛋白表达。SRD5A1-IN-1 (0-2.5 μM; 12 h) 通过影响 SRD5A1 蛋白表达水平和 SRD5A1 酶活性的双重作用调节 SRD5A1。
SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 μM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression.
体外研究：
SRD5A1-IN-1 (Compound 4) (0.5-2.5 μM; 24 h) 降低 SRD5A1 蛋白表达。SRD5A1-IN-1 (0-2.5 μM; 12 h) 通过影响 SRD5A1 蛋白表达水平和 SRD5A1 酶活性的双重作用调节 SRD5A1。
产品资料
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